o-Nitrophenol

  • 2-Nitrophenol
  • 2-Hydroxynitrobenzene
Formula
C6H5NO3
Structure
Description
Light yellow crystals with an aromatic odor.
Uses
Acid-base indicator. Corrosion inhibitor for aluminium-copper alloy.

Registry Numbers and Inventories.
CAS
88-75-5
EC (EINECS/ELINCS)
201-857-5
EC Class
irritant
R 20/22 33 36/37/38
S 26 36/37/39
RTECS
SM2100000
RTECS class
Other
UN (DOT)
1663
Merck
12,6717
Beilstein/Gmelin
775403
Beilstein Reference
4-06-00-01246
RCRA
K102
Swiss Giftliste 1
G-2650
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H5NO3
Formula mass
139.11
Melting point, °C
43 - 45
Boiling point, °C
214.6
Sublimation point, °C
30 (3 torr)
Vapor pressure, mmHg
0.093 (25 C)
Vapor density (air=1)
1.5
Odor Threshold Odor threshold 0.11-0.13 mg/m3
Density
1.599 g/cm3 (20 C)
Solubility in water
Soluble
Viscosity
2.31 cp (50 C)
Surface tension
42.3 g/s2 (50 C)
Refractive index
1.5723 (50 C)
Dipole moment
1.79 D
Dielectric constant
16.7 (60 C)
pKa/pKb
7.23 (pKa)
Partition coefficient, pKow
1.77
Heat of fusion
18.32 kJ/mol
Heat of vaporization
48.1 kJ/mol
Heat of combustion
-2871 kJ/mol

Hazards and Protection.
Storage
Tightly closed containers. Keep away from heat and water and from combustible organic or other readily oxidizable material.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible.
Respirators
For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Small spills/leaks
Sweep up, then place into a suitable container for disposal.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Halogen acids and strong oxidizing agents. In liquid/molten state, reacts violently with potassium hydroxide.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
97
Autoignition, °C
550
Fire fighting
Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Extinguishing agents: water, foam, dry chemical, carbon dioxide. Do not allow water runoff to enter sewers or waterways.
Fire potential
Combustible solid.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Toxic and irritating fumes of unburned material and oxides of nitrogen can form in fire.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
2
Exposure effects
Chronic exposure may damage the liver and kidneys.
   Ingestion
Toxic. Harmful if swallowed. Can cause formation of methemoglobin, resulting in cyanosis (blue lips), headaches, dizziness and collapse. Exposure to high concentrations may cause breathing trouble, a slow pulse, fall in blood pressure, convulsions and even death.
   Inhalation
Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath. Can be a route of absorption by the body with symptoms like ingestion.
   Skin
Causes irritation to skin. Symptoms include redness, itching, and pain. May be absorbed through the skin with possible systemic effects.
   Eyes
Causes irritation, redness, and pain.

First aid
 
   Ingestion
Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
1663
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
NTP
 
HS Code
2908 90 00
 
IMO Chemical Code
17
IMO Pollution Category
B
IMO Hazard code
S/P