- Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-
Triboluminescent, orthorhombic prisms from alcohol plus ether.
Registry Numbers and Inventories.
EC Index Number
Drug; Mutagen; Human Data
Japan ENCS (MITI)
Melting point, °C
200 - 201
Boiling point, °C
135-140 (11 torr)
Solubility in water
1.625 (20 C)
Hazards and Protection.
Optimal pH for storage of papaverinesolution: 2.0-2.8.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Sensitive to light and moisture.
Strong oxidizing agents.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Rapid heart rate and abnormally low blood pressure are common; low heart rate may occur. Both hyperpnea and apnea have been reported after rapid iv injection. lethargy and coma may occur. Dizziness and syncope have been reported following therapeutic use.
Nausea, vomiting, abdominal pain.
Hyperpnea, apnea, and respiratory alkalosis may occur.
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.