Pentachlorophenol

  • PCP
  • Penta
  • Penchlorol
Formula
C6HCl5O
Structure
Description
A white crystalline solid.
Uses
As a molluscicide, fungicide, herbicide, insecticide, plant growth regulator.

Registry Numbers and Inventories.
CAS
87-86-5
EC (EINECS/ELINCS)
201-778-6
EC Index Number
604-002-00-8
EC Class
Carcinogenic Category 3; Very toxic; Toxic; Irritant; Dangerous for the Environment
R 24/25 26 36/37/38 40 50/53
S 22 36/37 45 52 60 61
RTECS
SM6300000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
3155
Merck
12,7242
Beilstein/Gmelin
1285380
Beilstein Reference
4-06-00-01025
RCRA
D037
EPA OPP
600021
Swiss Giftliste 1
G-2068
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6HCl5O
Formula mass
266.34
Melting point, °C
188
Boiling point, °C
310
Vapor pressure, mmHg
0.0003 (25 C)
Vapor density (air=1)
1.98
Odor Threshold Odor threshold 1.6 mg/L.
Density
1.978 g/cm3 (22 C)
Solubility in water
10 mg/L
pKa/pKb
4.68 (pKa)
Partition coefficient, pKow
5.12
Heat of vaporization
57.2 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases, acid anhydrides, alkalies, acid chlorides, organic materials.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, chlorinated phenols.

Fire.
Flash Point,°C
134
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use extinguishing media most appropriate for the surrounding fire. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Generates toxic and irritating vapors.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 0.5 ppm; mg/m3 (as TWA) (skin) (ACGIH 1991-1992). MAK: class III A2; H (1993). OSHA PEL: TWA 0.5 mg/m3 skin NIOSH REL: TWA 0.5 mg/m3 skin NIOSH IDLH: 2.5 mg/m3
Carcinogin
G-A3, I-2B, CP65
Poison_Class
3
Exposure effects
Possible cancer hazard based on tests with laboratory animals. May cause liver and kidney damage. Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Chronic exposure has resulted in an increase prevalence of conjunctivitis, sinsuitis, bronchitis, polyneuritis, and dermatitis. Exposure may cuased blood effects and bone marrow damage. Chronic exposure may cause lung damage. Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May be fatal if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause effects similar to those of acute inhalation.
   Inhalation
May be fatal if inhaled. May cause increased perspiration, increased temperature, increased heart rate, increased breathing, weakness, nausea, vomiting, abdominal pain, headache, Systemic intoxication is cumulative and has been fatal. May cause violent sneezing and coughing. Inhalation may cuase damage to the circulatory system and heart and possible death due to cardiac failure. Causes irritation of the mucous membrane and upper respiratory tract.
   Skin
May be fatal if absorbed through the skin. Substance is rapidly absorbed through the skin. Causes symptoms similar to those of inhalation. Causes skin irritation and possible burns.
   Eyes
Causes eye irritation and possible burns. May cause visual damage, inflammation of the conjunctiva, corneal opacity and slight physiologic dilatation of the pupil.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3155
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
PCP
 
Std. Transport #
4921227