- R 125
- Ace 125
- Freon 125
- HFC 125
May be used as a replacement for chlorofluorocarbons.
Registry Numbers and Inventories.
S 23 38
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
9028 (20 C)
Vapor density (air=1)
1.53 g/cm3 (-48.5 C) (liquid)
Solubility in water
0.013 cp (25 C)
Partition coefficient, pKow
Hazards and Protection.
Stor in a dry, well-ventilated area, away from heat sources.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Wear appropriate chemical protective clothing.
Wear positive pressure self-contained breathing apparatus.
Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Stable under normal temperatures and pressures.
Incompatible with strong oxidizing and reducing agents Incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Oxides of carbon, hydrogen fluoride, carbonyl fluoride.
Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Do not use water on material itself. Use water spray to knock-down vapors.
May burn but does not ignite readily.
Containers may explode when heated. Ruptured cylinders may rocket.
All fluorocarbons will undergo thermal decomposition when exposed to flame or red-hot metal.
Headache, dizziness, and disorientation are common. Cerebral edema may be found on autopsy. Dichlorodifluoromethane was not teratogenic in rats and rabbits.
Nausea may develop. Ingestion of a small amount of trichlorofluoromethane resulted in necrosis and perforation of the stomach in one patient.
Pulmonary irritation, bronchial constriction, cough, dyspnea, and chest tightness may develop after inhalation. Chronic pulmonary hyperreactivity may occur. Adult respiratory distress syndrome has been reported following acute inhalational exposures. Pulmonary edema is an autopsy finding in fatal cases.
Dermal contact may result in defatting, irritation or contact dermatitis. Severe frostbite has been reported as an effect of freon exposure. Injection causes transient pain, erythema and edema.
EYES - Eye irritation occurs with ambient exposure. Frostbite of the lids may be severe. NOSE - Nasal irritation occurs with ambient exposure. THROAT - Irritation occurs. Frostbite of the lips, tongue, buccal mucosa and hard palate developed in a man after deliberate inhalation.
These substances may cause frostbite to the upper airway and gastrointestinal tract after ingestion. Administer oxygen and manage airway as clinically indicated. Emesis, activated charcoal, and gastric lavage are not recommended.
Provide a quiet calm atmosphere to prevent adrenaline surge if the patient is seen before the onset of cardiac arrhythmias. Minimize physical exertion.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. If frostbite has occurred, refer to dermal treatment in the main body of this document for rewarming.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Ophthamologic consultation should be obtained in any symptomatic patients.