Pentafluoroethane

  • 1,1,1,2,2-Pentafluoroethane
  • R 125
  • Ace 125
  • Freon 125
  • HFC 125
Formula
C2HF5
Structure
Description
Gas.
Uses
May be used as a replacement for chlorofluorocarbons.

Registry Numbers and Inventories.
CAS
354-33-6
EC (EINECS/ELINCS)
206-557-8
RTECS
KI6365000
RTECS class
Mutagen
UN (DOT)
3220
Beilstein/Gmelin
1698458
Beilstein Reference
4-01-00-00123
Swiss Giftliste 1
G-4109
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C2HF5
Formula mass
120.03
Melting point, °C
-103
Boiling point, °C
-48.5
Vapor pressure, mmHg
9028 (20 C)
Vapor density (air=1)
4.2
Critical temperature
66
Critical pressure
35.8
Density
1.53 g/cm3 (-48.5 C) (liquid)
Solubility in water
Slightly soluble
Viscosity
0.013 cp (25 C)
Partition coefficient, pKow
2.30

Hazards and Protection.
Storage
Stor in a dry, well-ventilated area, away from heat sources.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate chemical protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus.
Small spills/leaks
Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Incompatible with strong oxidizing and reducing agents Incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Decomposition
Oxides of carbon, hydrogen fluoride, carbonyl fluoride.

Fire.
Fire fighting
Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Do not use water on material itself. Use water spray to knock-down vapors.
Fire potential
May burn but does not ignite readily.
Hazards
Containers may explode when heated. Ruptured cylinders may rocket.
Combustion products
All fluorocarbons will undergo thermal decomposition when exposed to flame or red-hot metal.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
-
Exposure effects
Headache, dizziness, and disorientation are common. Cerebral edema may be found on autopsy. Dichlorodifluoromethane was not teratogenic in rats and rabbits.
   Ingestion
Nausea may develop. Ingestion of a small amount of trichlorofluoromethane resulted in necrosis and perforation of the stomach in one patient.
   Inhalation
Pulmonary irritation, bronchial constriction, cough, dyspnea, and chest tightness may develop after inhalation. Chronic pulmonary hyperreactivity may occur. Adult respiratory distress syndrome has been reported following acute inhalational exposures. Pulmonary edema is an autopsy finding in fatal cases.
   Skin
Dermal contact may result in defatting, irritation or contact dermatitis. Severe frostbite has been reported as an effect of freon exposure. Injection causes transient pain, erythema and edema.
   Eyes
EYES - Eye irritation occurs with ambient exposure. Frostbite of the lids may be severe. NOSE - Nasal irritation occurs with ambient exposure. THROAT - Irritation occurs. Frostbite of the lips, tongue, buccal mucosa and hard palate developed in a man after deliberate inhalation.

First aid
 
   Ingestion
These substances may cause frostbite to the upper airway and gastrointestinal tract after ingestion. Administer oxygen and manage airway as clinically indicated. Emesis, activated charcoal, and gastric lavage are not recommended.
   Inhalation
Provide a quiet calm atmosphere to prevent adrenaline surge if the patient is seen before the onset of cardiac arrhythmias. Minimize physical exertion.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. If frostbite has occurred, refer to dermal treatment in the main body of this document for rewarming.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Ophthamologic consultation should be obtained in any symptomatic patients.

Transport.
UN number
3220
Response guide
Hazard class
2.2
36. Halogenated hydrocarbons
Std. Transport #
4904318