Permethrin

  • 3-Phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
  • (3-Phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
  • m-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
Formula
C21H20Cl2O3
Structure
Description
Water white to pale yellow; colorless crystals to a viscous liquid.
Uses
Acaricide, insecticide.

Registry Numbers and Inventories.
CAS
52645-53-1
EC (EINECS/ELINCS)
258-067-9
EC Index Number
613-058-00-2
EC Class
Harmful
RTECS
GZ1255000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
2902
Merck
12,7321
Beilstein/Gmelin
2063148
EPA OPP
598600
Swiss Giftliste 1
G-96647
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C21H20Cl2O3
Formula mass
391.29
Melting point, °C
34
Boiling point, °C
466
Vapor pressure, mmHg
7E-9 (25 C)
Density
1.190-1.272 g/cm3 (20 C)
Solubility in water
Insoluble
Partition coefficient, pKow
6.50
Heat of vaporization
72.8 kJ/mol

Hazards and Protection.
Storage
Pyrethrins with piperonyl butoxide topical preparations should be stored in well-closed containers at a temperature less than 40C, preferably between 15-30C.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
No data.
Decomposition
When heated to decomposition it emits toxic fumes of hydrogen chloride.

Fire.
Flash Point,°C
159
Fire fighting
Use carbon dioxide, foam, or dry chemical on fires involving pyrethroids.
Fire potential
Non-Combustible
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
3
Exposure effects
   Ingestion
Nausea, vomiting and abdominal pain commonly occur and develop within 10 to 60 minutes following ingestion.
   Inhalation
Hypersensitivity reactions characterized by pneumonitis, cough, dyspnea, wheezing, chest pain, and bronchospasm may occur. Rare cases of respiratory failure and cardiopulmonary arrest have been reported.
   Skin
Irritant and contact dermatitis may develop. Erythema which mimics sunburn has also been noted after prolonged repeated exposure.
   Eyes
A stuffy, runny nose and scratchy throat following inhalational exposure may be noted.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Vitamin e topical application is highly effective in relieving paresthesias.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2902
Response guide
Hazard class
6.1
Packing Group
I; II; III