Phenacetamide

  • Benzeneacetamide
  • alpha-Phenylacetamide
  • 2-Phenylacetamide
  • Phenylacetic acid amide
  • Phenyl-beta-acetylamine
  • alpha-Toluamide
Formula
C8H9NO
Structure
Description
White crystalline solid.
Uses
Substance is used in production of penicillin G.

Registry Numbers and Inventories.
CAS
103-81-1
EC (EINECS/ELINCS)
203-147-0
RTECS
AC7705000
Merck
12,7420
Beilstein/Gmelin
507886
Beilstein Reference
4-09-00-01632
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H9NO
Formula mass
135.17
Melting point, °C
156 - 157
Boiling point, °C
312
Vapor pressure, mmHg
5.4E-4 (25 C)
Critical temperature
557
Critical pressure
41.9
Density
1.10 g/cm3
Solubility in water
Slightly soluble
Surface tension
33.7 g/s2 (160 C)
pKa/pKb
13.5 (pKb)
Partition coefficient, pKow
0.45
Heat of vaporization
55.32 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed and store in a cool, dry place away from incompatible chemicals.
Protection
Protective gloves and goggles.
Respirators
NIOSH/MSHA approved Respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area, wear appropriate protective equipment. Sweep up and place in appropriate container. Wash contaminated surfaces to remove any residue.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents and strong bases.
Decomposition
Decomposition liberates toxic fumes.

Fire.
Flash Point,°C
143
Fire fighting
Extinguish using CO2, dry chemical powder powder or water spray. Use NIOSH/MSHA approved SCBA and full protective equipment.

Health.
Exposure effects
   Ingestion
Harmful if swallowed.
   Inhalation
Can cause irritation of mucous membranes. Can cause cyanosis.
   Skin
Can be absorbed through skin causing irritation.
   Eyes
Can cause irritation.

First aid
 
   Ingestion
Seek immediate medical help.
   Inhalation
Move patient to fresh air. Administer oxygen if patient had difficulty breathing.
   Skin
If no burns have occured, use soap and water to cleanse skin.
   Eyes
Flush with water for 15 - 20 minutes.

Transport.