Phenarsazine oxide

  • bis(Phenoxarsin-10-yl) ether
  • bis(10-Phenoxarsinyl) oxide
  • bis(10-Phenoxarsyl) oxide
  • 10,10'-Oxybisphenoxyarsine
Formula
C24H16As2O3
Structure
Description
A clear light yellow liquid with a mild odor.
Uses
Fungicide, Microbiocide

Registry Numbers and Inventories.
CAS
58-36-6
EC (EINECS/ELINCS)
200-377-3
RTECS
SP6800000
RTECS class
Primary Irritant
Merck
12,7095
Beilstein/Gmelin
55641
Beilstein Reference
2-27-00-00948
RCRA
D004
EPA OPP
12601
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C24H16As2O3
Formula mass
502.23
Melting point, °C
184
Density
1.65 g/cm3
Solubility in water
5 ppm @ 20 C

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Keep material out of water sources and sewers. Build dikes to contain flow as necessary.
Stability
No data.
Incompatibilities
Incompatible with acids and bases Incompatible with oxidizing agents.

Fire.
Fire fighting
(Non-Specific -- Arsenic Compound, Solid, n.o.s.) Stay upwind; keep out of low areas. Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing.(Non-Specific -- Arsenic Compound, Solid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam. Move container from fire area if you can do so without risk.

Health.
Exposure effects
Abnormally low blood pressure and rapid heart rate may develop with acute arsenic poisoning. Toxic delirium and encephalopathy are complications of acute arsenic poisoning; encephalopathy may be permanent. Peripheral neuropathy leading to profound muscular weakness and wasting may be delayed by several weeks after acute exposure; recovery is usually slow or incomplete. No reproductive studies were found for OBPA, but arsenic compounds have been fetotoxic and teratogenic in animals. Arsenic can most likely cross the placenta. One neonatal fatality and several uneventful births have occurred in cases of acute arsenic poisoning in pregnancy. <br>Arsenic is excreted in the breast milk. Lower doses of arsenic have not affected male fertility in animals, but toxic doses have produced effects on the testes.
   Ingestion
Induction of vomiting is one of the bases for its use as a military agent. Gastroenteritis, sometimes with watery or bloody diarrhea, occurs with acute exposure to arsenic.
   Inhalation
Severe respiratory irritation leading to pulmonary edema would be expected from acute exposure to obpa. Respiratory failure and adult respiratory distress syndrome have occurred in acute arsenic intoxication.
   Eyes
Tearing and burns or strong irritation occur to the eyes. A garlic-like odor may be apparent on the breath.

First aid
 
   Ingestion
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove all exposed clothing and jewelry taking necessary precautions to prevent secondary exposure to health care providers. Irrigate exposed areas promptly with copious amounts of water for at least 30 minutes. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
Std. Transport #
4936208