Phenolphthalein

  • 3,3-bis(4-Hydoroxyphenyl)-1(3H)-isobenzofuranone
Formula
C20H14O4
Structure
Description
White or yellowish-white crystals, odorless.
Uses
Acid base indicator, laboratory reagent.

Registry Numbers and Inventories.
CAS
77-09-8
EC (EINECS/ELINCS)
201-004-7
S 22 36/37
RTECS
SM8380000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Human Data
UN (DOT)
1993
Merck
12,7392
Beilstein/Gmelin
284423
Beilstein Reference
5-18-04-00188
Swiss Giftliste 1
G-8474
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C20H14O4
Formula mass
318.33
Melting point, °C
258 - 262
Vapor density (air=1)
11
Evaporization number
Extremely low
Density
1.3 g/cm3
Solubility in water
0.092 g/L (20 C)
Refractive index
1.57 (7.9 C)
pKa/pKb
9.7 (pKa)
Partition coefficient, pKow
2.41

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
D2B
Handling
Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Carcinogin
I-2B, N-2, CP65
Poison_Class
3
Exposure effects
Possible cancer hazard based on tests with laboratory animals. Prolonged or repeated exposure may cause adverse reproductive effects. May cause kidney injury.
   Ingestion
May cause irritation of the digestive tract. Expected to be a low ingestion hazard.
   Inhalation
May cause respiratory tract irritation. Low hazard for usual industrial handling.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Get medical aid. Wash clothing before reuse. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1993
Response guide
21. Phenols. Cresols
HS Code
2932 29 10