Phentermine

  • 2-Amino-2-methyl-1-phenylpropane
  • alpha-Benzylisopropylamine
  • alpha-Benzylisopropylamine
  • alpha,alpha-Dimethylbenzeneethanamine
  • alpha,alpha-Dimethylphenethylamine
  • alpha,alpha-Dimethyl-beta-phenylethylamine
Formula
C10H15N
Structure
Description
Oily liquid.
Uses
Medication.

Registry Numbers and Inventories.
CAS
1197-21-3
EC (EINECS/ELINCS)
214-821-9
RTECS
SH4025000
RTECS class
Drug
Merck
12,7415
Beilstein/Gmelin
970319
Beilstein Reference
4-12-00-02820
RCRA
P046
Swiss Giftliste 1
G-4365
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C10H15N
Formula mass
149.24
Boiling point, °C
52 - 54 (0.3 - 0.5 torr)
Solubility in water
slightly soluble
Refractive index
1.5125 (20 C)

Hazards and Protection.
Storage
Keep in a cool, dry location in a tightly sealed container.
Handling
Where protective equipment when handling.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
NIOSH/MSHA approved respirator.
Small spills/leaks
Wear protective equipment. Sweep up or absorb and shovel into a bag for subsequent disposal. Provide adequate ventilation and wash site after pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen, oxides of carbon, oxides of nitrogen.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
3
Exposure effects
Severe elevated body temperature may develop. Elevated blood pressure and rapid heart rate are common. Agitation, confusion, paranoia, delirium, hallucinations, restlessness, hyperactivity, talkativeness, irritability, insomnia, and headache are common. Chorea, dystonia, fasciculations, muscle rigidity, tics, and tremors may develop. Seizures and coma may occur with severe intoxication. Other neurological effects have included stroke and cerebral vasculitis. Serotonin syndrome has occurred.
   Ingestion
Vomiting, diarrhea, cramps, anorexia and gastrointestinal hemorrhage may occur.
   Inhalation
Tachypnea is common. Pulmonary hypertension has been associated with chronic use or abuse which may result from contaminants. Pulmonary edema and ards are unusual complications of severe exposure.
   Skin
The skin is usually flushed and diaphoretic.
   Eyes
Irritation.

First aid
 
   Ingestion
Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.