Phosphoramidic acid, N,N-dibutyl, diethyl ester

  • N,N-Dibutylphosphoramidic acid diethyl ester
  • Diethyl-N,N-dibutylphosphoramidate
Formula
C12H28NO3P
Structure
Description
Brown liquid.

Registry Numbers and Inventories.
CAS
67828-17-5
EC (EINECS/ELINCS)
267-239-2
RTECS
TB2801500
RTECS class
Other
Beilstein/Gmelin
1786037
Beilstein Reference
4-04-00-00606
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C12H28NO3P
Formula mass
265.38
Boiling point, °C
115
Density
1.015 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.4299 (25 C)
pKa/pKb
8.05 (pKb)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
If Tyvek protective clothing is not worn during the handling of this chemical, wear disposable Tyvek sleeves taped to your gloves.
Respirators
Where the neat test chemical is stored, weighed and diluted, wear an approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA, (specific for organic vapors, HCl, acid gas SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This chemical is probably combustible.

Health.
Exposure effects
The toxicological properties of this material have not been investigated.

First aid
 
   Ingestion
CHOLINESTERASE INHIBITORS ARE EXTREMELY TOXIC AND FAST-ACTING POISONS. Atropine is an antidote for cholinesterase inhibitors but should only be administered by properly trained personnel. In the absence of this option and if the victim is conscious and not convulsing, it may be worth considering the risk of inducing vomiting, even though the induction of vomiting is not usually recommended outside of a physician's care. Ipecac syrup or salt water may be used to induce vomiting in such an emergency. IMMEDIATELY call a hospital or poison control center and transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.