Phthalylsulfacetamide

  • 2-([(4-([Acetylamino]sulfonyl)phenyl)amino]carbonyl)benzoic acid
  • 4'-(Acetylsulfamyl)phthalanilic acid
  • 4'-(Acetylsulfamoyl)phthalanilic acid
  • Sulphalyl
  • Talasulfa
  • Enterosulfon
Formula
C16H14N2O6S
Structure

Registry Numbers and Inventories.
CAS
131-69-1
EC (EINECS/ELINCS)
205-035-7
Merck
12,7532
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed

Properties.
Formula
C16H14N2O6S
Formula mass
362.36
Melting point, °C
196
Boiling point, °C
280 - 282
Density
1.48 g/cm3 (20 C)
Solubility in water
0.35 g/L (25 C)
pKa/pKb
3.40 (pKa)
Partition coefficient, pKow
0.31

Hazards and Protection.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Wear appropriate government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperratures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
May cause irritation. May be harmful by inhalation, ingestion, or skin absorption. Possibility of crossover sensitization to sulfonamides may cause salivation, hyperpnea, excitement, muscular weakness, ataxia, athetotoic movements, clonic convulsions, paralysis, death from respiratory failure.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.