Picolinic acid

  • 2-Carboxypyridine
  • 2-Pyridylcarboxylic acid
  • o-Pyridinecarboxylic acid
  • 2-Pyridinecarboxylic acid
  • a-Pyridinecarboxylic acid
Formula
2-(HOOC)C5H4N
Structure
Description
White solid.
Uses
Natural chelator of the vital trace elements chromium, zinc, manganese, copper, iron, and molybdenum.

Registry Numbers and Inventories.
CAS
98-98-6
EC (EINECS/ELINCS)
202-719-7
EC Class
irritant
R 22 36/37/38
S 26 36/37/39
RTECS
TJ7344000
RTECS class
Other
Merck
12,7557
Beilstein/Gmelin
109595
Beilstein Reference
5-22-02-00003
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H5NO2
Formula mass
123.11
Melting point, °C
134 - 137
Boiling point, °C
293
Vapor pressure, mmHg
0.001 (25 C)
Density
1.49 g/cm3
Solubility in water
Very soluble
pKa/pKb
0.92 (pKa)
Partition coefficient, pKow
0.81
Heat of fusion
14.5 kJ/mol
Heat of vaporization
56.2 kJ/mol
Heat of combustion
-2738 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, bases, oxidizing agents, reducing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
131
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Health.
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
The toxicological properties of this substance have not been fully investigated.
   Skin
No information regarding skin irritation and other potential effects was found.
   Eyes
No information regarding eye irritation and other potential effects was found.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2933 39 99