Piperazine

  • Hexahydropyrazine
  • Piperazidine
Formula
C4H10N2
Structure
Description
Colorless to white to off-white crystals, mild ammoniacal or fishy odor, deliquescent.
Uses
Corrosion inhibitor, insecticides, accelerator for curing polychloroprene.

Registry Numbers and Inventories.
CAS
110-85-0
EC (EINECS/ELINCS)
203-808-3
EC Index Number
612-057-00-4
EC Class
Corrosive; Sensitising; Dangerous for the Environment
R 34 42/43 52/53
S 22 26 36/37/39 45 61
RTECS
TK7800000
RTECS class
Agricultural Chemical and Pesticide; Drug; Human Data; Primary Irritant
UN (DOT)
2579
Merck
12,7617
Beilstein/Gmelin
102555
Beilstein Reference
5-23-01-00030
Swiss Giftliste 1
G-2756
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H10N2
Formula mass
86.14
Melting point, °C
44 - 46
Boiling point, °C
146
Vapor pressure, mmHg
4.1 (25 C)
Vapor density (air=1)
3
Saturation Concentration
211 ppm (0.02%) at 20 C (calculated)
Critical temperature
388
Critical pressure
57.24
Density
1.26 g/cm3 (25 C)
Solubility in water
Very soluble
Refractive index
1.446 (113 C)
pKa/pKb
4.11 (pKb)
Partition coefficient, pKow
-1.17
Heat of fusion
26.7 kJ/mol
Heat of vaporization
50.1 kJ/mol
Heat of combustion
-2962 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Store in a cool, dry place. Corrosives area.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get on skin or in eyes. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up, then place into a suitable container for disposal.
Disposal code
5
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents; strong acids; acid chlorides; acid anhydrides; light; moisture; dicyanofurazan.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
50
Autoignition, °C
320
Upper exp. limit, %
14
Lower exp. limit, %
4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
May burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Prolonged or repeated skin contact may cause sensitization dermatitis and possible destruction and/or ulceration. Prolonged or repeated exposure may cause permanent eye damage. Repeated exposure may cause allergic respiratory reaction (asthma).
   Ingestion
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
   Inhalation
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. May cause asthmatic attacks due to allergic sensitization of the respiratory tract. Causes chemical burns to the respiratory tract.
   Skin
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Contact with skin causes irritation and possible burns, especially if the skin is wet or moist.
   Eyes
Contact with eyes may cause severe irritation, and possible eye burns.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Get medical aid immediately. Gently lift eyelids and flush continuously with water.

Transport.
UN number
2579
Response guide
Hazard class
8
Packing Group
III
 
USCG CHRIS Code
PPZ
 
HS Code
2933 59 95
 
Std. Transport #
4936608