Piperidine

  • Hexahydropyridine
  • Pentamethyleneimine
  • Azacyclohexane
Formula
C5H11N
Structure
Description
Clear, colorless liquid, amine-like pungent odor.
Uses
Prepn of crystalline derivatives of aromatic nitro compd containing nuclear halogen atoms.

Registry Numbers and Inventories.
CAS
110-89-4
EC (EINECS/ELINCS)
203-813-0
EC Index Number
613-027-00-3
EC Class
Highly flammable; Toxic; Corrosive
R 11 23/24 34
S 16 26 27 45
RTECS
TM3500000
RTECS class
Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
2401
Merck
12,7621
Beilstein/Gmelin
102438
Beilstein Reference
5-20-02-00003
Swiss Giftliste 1
G-2757
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C5H11N
Formula mass
85.15
Melting point, °C
-10
Boiling point, °C
107.3
Vapor pressure, mmHg
23 (20 C)
Vapor density (air=1)
3.0(AIR=1)
Saturation Concentration
52600 ppm (5.3%) at 29.2 C (calculated)
Critical pressure
45.9
Density
0.8622 g/cm3 (20 C)
Solubility in water
Very soluble
Viscosity
1.31 cp (25 C)
Surface tension
29.75 g/s2 (25 C)
Refractive index
1.4534 (20 C)
Dipole moment
1.15 D (20 C)
Dielectric constant
5.8 (22 C)
pKa/pKb
3.76 (pKb)
Partition coefficient, pKow
0.84
Heat of fusion
11.4 kJ/mol
Heat of vaporization
39.3 kJ/mol
Heat of combustion
-3453 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. Flammables-area.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids; acid chlorides; acid anhydrides; carbon dioxide; strong oxidizing agents; dicyanofurazan; N-nitrosoacetanilide; 1-Perchlorylpiperdine
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
16
Autoignition, °C
320
Upper exp. limit, %
10.3
Lower exp. limit, %
1.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. Can release vapors that form explosive mixtures at temperatures above the flashpoint. To extinguish fire use water fog, dry chemical, carbon dioxide or alcohol type foam.
Fire potential
Quite flammable.
Hazards
Piperidine evolves explosive concentrations of vapor at normal room temperatures. When heated to decomposition, it emits highly toxic fumes of nitrogen oxides. Dangerous, when exposed to heat, flame, or oxidizers. Avoid 1-Perchlorylpiperidine and oxidizing materials. Piperidine is a reactive compound and forms complexes with the salts of heavy metals. It evolves explosive concentrations of vapor at normal room temperatures. Keep away from igniting sources and heat.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
3
 
 
Reactivity
0
 

Health.
Poison_Class
2
Exposure effects
Repeated inhalation may cause chronic bronchitis. Prolonged or repeated contact may cause skin necrosis and/or ulceration of the skin. May cause chronic cough.
   Ingestion
Harmful if swallowed. Causes gastrointestinal tract burns. Can cause nervous system damage. May cause tremors and convulsions.
   Inhalation
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract.
   Skin
Harmful if absorbed through the skin. Penetration may continue for several days. Causes skin irritation and possible severe skin irritation especially if the skin is wet or moist.
   Eyes
Causes eye irritation. Contact with liquid or vapor causes severe burns and possible irreversible eye damage. Eye damage may be delayed. May cause blindness.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes). SPEEDY ACTION IS CRITICAL!

Transport.
UN number
2401
Response guide
Hazard class
8
Packing Group
I
 
USCG CHRIS Code
PRN
 
HS Code
2933 32 00
 
Std. Transport #
4910549