Piperonyl sulfoxide

  • Isofrol-n-octyl sulfoxide
  • Isosafrole n-octylsulfoxide
  • 1,2-(methylenedioxy)-4-(2-(Octylsulfinyl)propyl)benzene
  • 1-Methyl-2-(3,4-Methylenedioxyphenyl)ethyl octyl sulfoxide
  • n-Octylisosafrole sulfoxide
  • 5-(2-(Octylsulfinyl)propyl)-1,3-benzodioxole
Formula
C18H28O3S
Structure
Description
Clear pale yellow to amber viscous liquid with a sweetish smell.
Uses
Insecticide synergist used with pyrethrins and allethrin.

Registry Numbers and Inventories.
CAS
120-62-7
EC (EINECS/ELINCS)
204-412-3
RTECS
DA5775000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector
Merck
12,9140
Beilstein/Gmelin
NA
EPA OPP
57101
Swiss Giftliste 1
G-2863

Properties.
Formula
C18H28O3S
Formula mass
324.48
Boiling point, °C
136-139 (2 torr)
Density
1.06 g/cm3 (25 C)
Solubility in water
practically insoluble

Hazards and Protection.
Storage
Keep in well ventilated area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
Stable under normal conditions very stable even to acids and bases (at room temperature) technical 88%.
Incompatibilities
Reacts violently with perchloric acid.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This chemical is probably combustible.

Health.
Poison_Class
4
Exposure effects
One case of pathological laughter has been reported with human exposure. Primary sources of data are from animals which include reports of hyperexcitability, unsteadiness, coma, seizures, and brain damage in large overdoses. Mixed results for teratogenicity have been obtained in animals.
   Ingestion
Nausea, vomiting, anorexia, or diarrhea may be seen.
   Inhalation
Symptoms of exposure to this compound may include tremors, central nervous system depression and prolonged coma 10 to 20 minutes after exposure.
   Skin
Skin irritation or significant percutaneous absorption is not expected following normal dermal exposure.
   Eyes
See inhalation

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.