Pregnan-3a-ol-20-one

  • Pregnan-20-one, 3-hydroxy-, (3a,5b)-
  • Pregnanolone II
  • 3a-Hydroxy-5b-tetrahydroprogesterone
  • 3a,5b-Tetrahydroprogesterone
Formula
C21H34O2
Structure
Description
Solid.

Registry Numbers and Inventories.
CAS
128-20-1
RTECS
TU4384000
Merck
12,7910
Beilstein/Gmelin
4785659

Properties.
Formula
C21H34O2
Formula mass
318.5
Melting point, °C
149.5
Boiling point, °C
431
Vapor pressure, mmHg
3.1E-9 (25 C)
Density
1.05 g/cm3 (20 C)
Solubility in water
2.3 mg/L (25 C)
pKa/pKb
15.11 (pKa)
Partition coefficient, pKow
4.89
Heat of vaporization
79.26 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Wear appropriate government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Oxides of carbon

Fire.
Flash Point,°C
183
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
0
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.