Procainamide hydrochloride

  • Novocaine amide hydrochloride
  • Pronestyl hydrochloride
  • Spicain amide
  • Cardiorytmin
  • 4-Amino-N-[2-(diethylamino)ethyl]benzamide monohydrochloride
  • Benzamide, 4-amino-N-[2-(diethylamino)ethyl]-, monohydrochloride
Formula
C13H21N3O.HCl
Structure
Description
White solid.
Uses
Used to control irregular heart beats (arrhythmias).

Registry Numbers and Inventories.
CAS
614-39-1
EC (EINECS/ELINCS)
210-381-7
RTECS
CV2295000
RTECS class
Drug; Human Data
Merck
12,7936
Beilstein/Gmelin
3729517
Beilstein Reference
4-14-00-01154
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed

Properties.
Formula
C13H21N3O*ClH
Formula mass
271.79
Melting point, °C
167

Hazards and Protection.
Storage
Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store and handle protected from air.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
May decompose when exposed to light.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.

Health.
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.