Profenofos

  • Curacron
  • O-(4-Bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate
  • O-Ethyl-S-n-propyl-O-(2-chloro-4-bromophenyl)thiophosphate
  • O-Ethyl S-propyl O-(2-chloro-4-bromophenyl)thiophosphate
Formula
C11H15BrClO3PS
Structure
Description
Pale yellow liquid with garlic-like odor.
Uses
Control of insects and mites. Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses.

Registry Numbers and Inventories.
CAS
41198-08-7
EC (EINECS/ELINCS)
255-255-2
EC Index Number
015-135-00-0
20/21/22
RTECS
TE6975000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Human Data
UN (DOT)
2810
Beilstein/Gmelin
2150258
Beilstein Reference
6-06
EPA OPP
210700
Swiss Giftliste 1
G-4922
Austrailia AICS
Listed
Korea ECL
Listed

Properties.
Formula
C11H15BrClO3PS
Formula mass
373.65
Boiling point, °C
402
Vapor pressure, mmHg
2.7E-6 (25 C)
Solubility in water
28 mg/L (25 C)
Refractive index
1.5466 (20 C)
Heat of vaporization
62.8 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store at 2-8 C
Protection
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Absorb on sand or vermiculite and place in closed containers for disposal. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Alkaline conditions. Oxidizing and reducing agents.
Decomposition
Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Fire.
Flash Point,°C
197
Fire fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Sulfur oxides, phosphorus oxides, hydrogen bromide and hydrogen chloride.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Harmful by inhalation, in contact with skin and if swallowed. Readily absorbed through skin. Target organ(s): Blood. Heart.
   Ingestion
See inhalation.
   Inhalation
Profenofos can cause cholinesterase inhibition in humans; that is, it can stimulate the nervous system causing nausea, dizziness, confusion and at very high exposures (e.g., accidents or major spills), respiratory paralysis and death.
   Skin
See inhalation.
   Eyes
See inhalation.

First aid
 
   Ingestion
Rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal .
   Inhalation
Establish a patient airway. Suction if necessaryAggressive airway control may be needed. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary. Monitor for shock and treat if necessary Anticipate seizures and treat if necessary .
   Skin
Flush exposed area with water, wash with soap and water. Monitor for symptoms.
   Eyes
Flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport to medical facility

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
II