Proflavine hemisulfate

  • 3,6-Diaminoacridine hemisulfate
  • Acridine, 3,6-diamino-, sulfate (2:1)
Formula
C13H11N3.H2SO4
Structure
Description
Orange to red powder.
Uses
Antibacterial.

Registry Numbers and Inventories.
CAS
1811-28-5
EC (EINECS/ELINCS)
217-320-3
RTECS
AR9065100
RTECS class
Tumorigen; Drug; Mutagen
Beilstein/Gmelin
3921806
Beilstein Reference
5-22-11-00323
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed

Properties.
Formula
C13H11N3*H2O4S
Formula mass
307.32

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store protected from light.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. Use only in a chemical fume hood. Wash clothing before reuse. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. Light sensitive.
Incompatibilities
Moisture, direct light, strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
1
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.