Pronamide

  • 3,5-Dichloro-n-(1,1-dimethylpropynyl)benzamide
  • 3,5-Dichloro-n-(1,1-dimethyl-2-propynyl)benzamide
  • N-(1,1-Dimethylpropynyl)-3,5-dichlorobenzamide
  • Kerb
  • Promamide
  • Pronamid
Formula
C12H11Cl2NO
Structure
Description
White solid.
Uses
Selective herbicide that will control many broadleaf & grass weeds preemergence in lettuce and other crops.

Registry Numbers and Inventories.
CAS
23950-58-5
EC (EINECS/ELINCS)
245-951-4
EC Index Number
616-055-00-4
EC Class
Carcinogenic Category 3; Dangerous for the Environment
RTECS
CV3460000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen
Merck
12,8058
Beilstein/Gmelin
882391
RCRA
U192
EPA OPP
101701
Swiss Giftliste 1
G-7005
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C12H11Cl2NO
Formula mass
256.13
Melting point, °C
155
Boiling point, °C
321
Vapor pressure, mmHg
8E-5 (25 C)
Solubility in water
15 mg/L (25 C)
pKa/pKb
12.30 (pKa)
Partition coefficient, pKow
3.43
Heat of vaporization
58.5 kJ/mol

Hazards and Protection.
Storage
No special storage problems under normal ambient conditions. In a two-year storage trial under normal conditions, there was no decomposition. Storage at high temperature should be avoided.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
. General percautions: take special care to avoid contact with the eyes, skin, or clothing. Wash clothing and gloves after use. Protective clothing: the following items of clothing are required when mixing or applying pronamide: a) long-sleeved shirts and long pants, preferably one piece (overalls). B) hat with brim. C) heavy duty fabric or rubber work gloves.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No decomp in 2-yr storage trial under normal conditions.
Incompatibilities
Strong oxidizing agents.

Fire.
Flash Point,°C
160
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Fire potential
Flammability not a problem.

Health.
Carcinogin
CP65
Poison_Class
-
Exposure effects
The toxicological properties of this material have not been investigated.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
USCG CHRIS Code
PNM