Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2- methyl-, (+-)

  • Bicalutamide
  • Casodex
  • ICI-176334
Formula
C18H14F4N2O4S

Registry Numbers and Inventories.
CAS
90357-06-5
RTECS
TX1413500
Merck
12,1247
Beilstein/Gmelin
5364666

Properties.
Formula
C18H14F4N2O4S
Formula mass
430.38
Melting point, °C
191-193
Vapor pressure, mmHg
8.5E-18 (25 C)
Density
1.52 g/cm3 (20 C)
pKa/pKb
11.49 (pKa)
Partition coefficient, pKow
4.94

Hazards and Protection.
Storage
Store in original container in a cool dark place.
Protection
Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.
Small spills/leaks
Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.

Fire.
Fire fighting
Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.
Combustion products
Emits toxic fumes under fire conditions.

Health.
Exposure effects

First aid
 
   Ingestion
If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.
   Inhalation
Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.
   Skin
Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.
   Eyes
Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.

Transport.