Propargylic acid

  • Propiolic acid
  • Carboxyacetylene
  • 2-Propynoic acid
  • Acetylenecarboxylic acid
  • 2-Propyne-1-carboxylic acid
  • Acetylenemonocarboxylic acid
Formula
C3H2O2
Structure
Description
Clear yellow to orange liquid. Acetic odor.

Registry Numbers and Inventories.
CAS
471-25-0
EC (EINECS/ELINCS)
207-437-8
EC Class
toxic, corrosive
R 24/25 34 36/37
S 26 36/37/39 45
RTECS
UD9300000
RTECS class
Other
UN (DOT)
1760
Merck
12,8006
Beilstein/Gmelin
878176
Beilstein Reference
4-02-00-01687
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C3H2O2
Formula mass
70.05
Melting point, °C
18
Boiling point, °C
140
Vapor pressure, mmHg
3.7 (25 C0
Vapor density (air=1)
2.42
Density
1.1499 g/cm3 (4 C)
Solubility in water
Very soluble
Surface tension
36.28 g/s2 (25 C)
Refractive index
1.4302 (20 C)
pKa/pKb
1.99 (pKa)
Partition coefficient, pKow
0.31 kJ/mol
Heat of vaporization
41.6 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Flammables-area. Refrigerator (approx 4 C). Keep containers tightly closed. Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Moisture, bases, oxidizing agents, reducing agents, copper (I) + ammonia, silver salts + ammonia.
Decomposition
Carbon monoxide, carbon dioxide, acrid smoke and fumes.

Fire.
Flash Point,°C
58
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
   Inhalation
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Vapors may cause dizziness or suffocation. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
   Skin
May cause severe irritation and possible burns. May cause dermatitis. Substance is readily absorbed through the slkin. May cause cyanosis of the extremities.
   Eyes
Contact with eyes may cause severe irritation, and possible eye burns. Lachrymator. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
1760
Response guide
Hazard class
8
Packing Group
I; II; III
 
HS Code
2916 19 80