Propentophylline

  • 1-(5-Oxohexyl)-3-methyl-7-propylxanthine
  • 3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione
  • Hextol
  • Albert-285
  • Propentofylline
  • Karsivan
Formula
C15H22N4O3
Structure

Registry Numbers and Inventories.
CAS
55242-55-2
R: 20/21/22
RTECS
UO8438700
Merck
12,7997
Beilstein/Gmelin
1156290
Beilstein Reference
5-26-14-00082
New Zealand
Listed

Properties.
Formula
C15H22N4O3
Formula mass
306.36
Melting point, °C
69
Boiling point, °C
541
Vapor pressure, mmHg
8.7E-12 (25 C)
Density
1.25 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
13.16 (pKb)
Partition coefficient, pKow
1.38
Heat of vaporization
81.9 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store at -20 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable if stored as recommended.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
281
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Combustion products
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful by inhalation, in contact with skin and if swallowed.
   Ingestion
Harmful if swallowed.
   Inhalation
Harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause irritation. Harmful if absorbed through the skin.
   Eyes
May cause irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.