Propyl gallate

  • NIPA 49
  • Nipagallin p
  • Progallin p
  • n-Propyl gallate
  • n-Propyl 3,4,5-Trihydroxybenzoate
  • Propyl 3,4,5-Trihydroxybenzoate
Formula
C10H12O5
Structure
Description
Fine white to creamy-white crystalline powder. Odorless or with a faint odor. Slightly bitter taste.
Uses
Antioxidant or synergist to retard or prevent rancidity in lard & other edible fats & oils, laboratory reagent.

Registry Numbers and Inventories.
CAS
121-79-9
EC (EINECS/ELINCS)
204-498-2
EC Index Number
607-198-00-3
EC Class
Harmful; Sensitising
R 22 43
RTECS
LW8400000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector
Merck
12,8044
Beilstein/Gmelin
1877976
Beilstein Reference
4-10-00-02003
Swiss Giftliste 1
G-2228
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C10H12O5
Formula mass
212.20
Melting point, °C
145 - 148
Boiling point, °C
449
Vapor pressure, mmHg
1E-8 (25 C)
Density
1.21 g/cm3 (20 C)
Solubility in water
3.5 g/L (25 C)
Refractive index
1.5204 (167 C)
pKa/pKb
7.82 (pKa)
Partition coefficient, pKow
2.60
Heat of vaporization
75.4 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong bases, strong oxidizing agents, strong reducing agents, strong acids.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
181
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
This chemical is combustible.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2918 29 50