Propylene glycol

  • 1,2-Dihydroxypropane
  • Methyl ethylene glycol
  • 1,2-Propanediol
  • Propane-1,2-diol
Formula
CH3CH(OH)CH2OH
Structure
Description
Clear, viscous, colorless liquid, practically odorless, hygroscopic.
Uses
Component of cellophane.

Registry Numbers and Inventories.
CAS
57-55-6
EC (EINECS/ELINCS)
200-338-0
RTECS
TY2000000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Human Data; Primary Irritant
Merck
12,8040
Beilstein/Gmelin
1340498
Beilstein Reference
3-01-00-02142
EPA OPP
68603
Swiss Giftliste 1
G-2798
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H8O2
Formula mass
76.10
Melting point, °C
-59
Boiling point, °C
187.6
Vapor pressure, mmHg
0.2 (23 C)
Vapor density (air=1)
2.62
Saturation Concentration
Approximately 90-260 ppm at 20 C (calc.)
Evaporization number
0.005 (butyl acetate = 1)
Odor Threshold Odor threshold Odorless
Critical temperature
403
Critical pressure
58.63
Density
1.04 g/cm3 (20 C)
Solubility in water
Miscible
Viscosity
91.41 cp (10.45 C)
Surface tension
40.1 g/s2 @ 25 C
Refractive index
1.4324 (20C)
Partition coefficient, pKow
-0.92
Heat of vaporization
66.27 kJ/mol
Heat of combustion
-1828 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Insufficient information
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents, reducing agents, acid chlorides, nitric acid, acid anhydrides, silver nitrate, hydrofluoric acid, chloroformates, moisture.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acetic acid, propionaldehyde, lactic acid, pyruvic acid.

Fire.
Flash Point,°C
99
Autoignition, °C
371
Upper exp. limit, %
17.4
Lower exp. limit, %
2.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use alcohol foam. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
This chemical is combustible.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
-
Exposure effects
May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects. Exposure to large doses may cause central nervous system depression. Chronic ingestion may cause lactic acidosis and possible seizures.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Low hazard for usual industrial handling. May cause hemoglobinuric nephrosis. May cause changes in surface EEG.
   Inhalation
Low hazard for usual industrial handling. May cause respiratory tract irritation.
   Skin
Causes moderate skin irritation. Contact with the skin may cause erythema, dryness, and defatting.
   Eyes
Causes mild eye irritation. Contact may cause irritation, tearing, and burning pain.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
USCG CHRIS Code
PPG
 
20 Alcohols, Glycols
HS Code
2905 32 00
 
IMO Chemical Code
18
IMO Pollution Category
III