Propyleneimine

  • 2-Methylazidirine
  • Methylethylenimine
  • Propylene imine
Formula
C3H7N
Structure
Description
A clear, colorless, oily liquid with an ammonia-like odor.
Uses
Chemical intermed in modification of latex surface coating resins, polymers in textile and paper indust, dyes, chemical intermed in photography, gelatins and for oil additives, comonomer for polymer with methacrylic acid & esters, Chemical intermediate for tris(2-methyl-1-aziridinyl)-1,3,5-triazine.

Registry Numbers and Inventories.
CAS
75-55-8
EC (EINECS/ELINCS)
200-878-7
EC Index Number
613-033-00-6
EC Class
Highly flammable; Carcinogenic Category 2; Very toxic; Irritant; Dangerous for the Environment
RTECS
CM8050000
RTECS class
Tumorigen; Mutagen
UN (DOT)
1921
Beilstein/Gmelin
102386
Beilstein Reference
5-20-01-00150
RCRA
P067
Swiss Giftliste 1
G-2806
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C3H7N
Formula mass
57.11
Melting point, °C
-65
Boiling point, °C
66
Vapor pressure, mmHg
151 (25 C)
Vapor density (air=1)
2.0
Critical temperature
266
Critical pressure
55
Density
0.812 g/cm3 (16 C)
Solubility in water
Miscible
Surface tension
25 g/s2
Refractive index
1.4112 (22.5 C)
pKa/pKb
5.78 (pKb)
Partition coefficient, pKow
-0.29
Heat of vaporization
30.8 kJ/mol
Heat of combustion
-1910 kJ/mol

Hazards and Protection.
Storage
Always store over solid alkali to avoid violent polymerization from contact with acids or acid fumes. Stable if kept in contact with solid caustic soda. Store at ambient temperature, exclude air, and use pressure vacuum venting. Preserve in well-closed, light-resistant containers.
B2 D1A D2A
Handling
Handle in accordance with all current regulations and standards.
Protection
Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.
Respirators
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode.
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid. Apply water spray or mist to knock down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Water spill: Use natural barriers or oil spill control booms to limit spill travel. Remove trapped material with suction hoses.
Stability
Violent polymerization upon contact with acids or acid fumes may be explosive. Container may explode in heat of fire. Vapor explosion (and poison) hazard indoors, outdoors, or in sewers. Runoff to sewers may create fire or explosion hazard. Polymerizes easily.
Incompatibilities
Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.

Fire.
Flash Point,°C
-15
Upper exp. limit, %
15.1
Lower exp. limit, %
2.3
Fire fighting
If material is on fire, do not extinguish fire unless flow can be stopped. Use water in flooding quantities as a fog and use to cool all affected containers. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Isolate for 1/2 mile in all directions if tank car or truck is involved in fire.If material is on fire, use foam, carbon dioxide, or dry chemical.
Fire potential
Flammable.
Hazards
Chemical is extremely flammable; vapors are heavier than air. Toxic oxides of nitrogen are produced during combustion. Avoid acids, strong oxidizers. Thermally unstable. Hazardous polymerization may occur. Contact with acid promotes violent polymerization.
Combustion products
Toxic gases and vapors (such as oxides of nitrogen and carbon monoxide) may be released in a fire involving propyleneimine.

Health.
Exposure limit(s)
OSHA PEL: TWA 2 ppm (5 mg/m3) skin NIOSH REL: Ca TWA 2 ppm (5 mg/m3) skin See Appendix A NIOSH IDLH: Potential occupational carcinogen 100 ppm
Carcinogin
G-A3, I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
Unspecified CNS effects may occur. No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation. <br>No information about possible male reproductive effects was found in available references.
   Ingestion
Delayed onset of vomiting may occur.
   Inhalation
Noncardiogenic pulmonary edema and respiratory irritation may occur from inhalation of oxides of nitrogen released by combustion or thermal degradation.
   Skin
Contact allergy to paint and plastic hardeners produced by reacting propylene imine with polyfunctional acrylates may occur.
   Eyes
Eye irritation occurs from exposure to vapor. Direct eye contact has produced corneal injury. Nose and throat irritation can occur.

First aid
 
   Ingestion
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. If direct eye contact with the liquid occurs, prolonged flushing and early ophthalmologic consultation may be advisable. Treatment should include recommendations listed in the inhalation exposure section when appropriate.

Transport.
UN number
1921
Response guide
Hazard class
3
Packing Group
I
 
USCG CHRIS Code
PII
 
Std. Transport #
4907040