Purine-6-thiol, monohydrate

  • 1,7-Dihydro-6H-purine-6-thione-monohydrate
  • 1,7-Dihydro-6H-purin-6-thion, monohydrat
  • 6-Mercaptopurine-monohydrate
  • 6-Merkaptopurin, monohydrat
  • 6H-Purine-6-thione, 1,7-dihydro-, monohydrate
  • Purin-6-thiol, monohydrat
Formula
C5H4N4S.H2O
Structure
Description
Odorless light yellow to yellow crystalline powder.

Registry Numbers and Inventories.
CAS
6112-76-1
EC (EINECS/ELINCS)
200-037-4
EC Class
harmful
R 61 22
RTECS
UP0400000
RTECS class
Mutagen; Reproductive Effector
UN (DOT)
2811
Merck
13,5896
Beilstein/Gmelin
4012091

Properties.
Formula
C5H4N4S . H2O
Formula mass
170.19
Melting point, °C
315 - 319
Solubility in water
insoluble

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong acids, strong bases.
Decomposition
Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This material is probably combustible.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May cause reproductive and fetal effects.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause respiratory tract irritation. May cause irritation of the mucous membranes.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2811
Response guide
HS Code
2933 59 95