Pyrazon

  • Chloridazone
  • Pyramin
  • 5-Amino-4-chloro-2-phenyl-3(2H)-pyridazinone
  • 1-Phenyl-4-amino-5-chloropyridazone-6
  • (2H)-Pyridazinone, 5-Amino-4-chloro-2-phenyl
  • 5-Amino-4-chloro-2,3-dihydro-3-oxo-2-phenylpyridazine
Formula
C10H8ClN3O
Structure
Description
Colorless solid. Almost odorless (technical).
Uses
Pre- and post-emergence herbicide.

Registry Numbers and Inventories.
CAS
1698-60-8
EC (EINECS/ELINCS)
216-920-2
EC Index Number
606-035-00-3
EC Class
Sensitising; Dangerous for the Environment
RTECS
UR6125000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Primary Irritant
Beilstein/Gmelin
397241
Beilstein Reference
5-25-14-00196
EPA OPP
129182
Swiss Giftliste 1
G-2817
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C10H8ClN3O
Formula mass
221.66
Melting point, °C
210
Density
1.54 g/cm3 (20 C)
Solubility in water
400 mg/L (20 C)
pKa/pKb
12.01 (pKb)
Partition coefficient, pKow
1.14

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Stable up to 50 C for > =2 yr. Stable in aqueous media at pH 3-9.Disappearance half-life in simulated sunlight 150 hr (ph 7, water). Stable stable in acid media.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Fire potential
Dry powder, nonflammable.

Health.
Poison_Class
4
Exposure effects
The toxicological properties of this material have not been investigated.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Pesticides - remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Irritation - treat dermal irritation or burns with standard topical therapy
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.