Pyrene

  • Benzo[def]phenanthrene
Formula
C16H10
Structure
Description
Colorless or yellow crystalline solid.
Uses
Biochemical research.

Registry Numbers and Inventories.
CAS
129-00-0
EC (EINECS/ELINCS)
204-927-3
S 22 24/25
RTECS
UR2450000
RTECS class
Tumorigen; Mutagen; Primary Irritant
UN (DOT)
1325
Merck
12,8147
Beilstein/Gmelin
1307225
Beilstein Reference
4-05-00-02467
RCRA
K001; U051
Swiss Giftliste 1
G-2818
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C16H10
Formula mass
202.26
Melting point, °C
148 - 150
Boiling point, °C
404
Vapor pressure, mmHg
0.5 (150 C)
Critical temperature
665
Critical pressure
25.7
Density
1.27 g/cm3
Solubility in water
1 mg/L
Viscosity
0.97 cp (20 C)
Surface tension
37.24 g/s2 (20 C)
Refractive index
1.5102 (20 C)
Partition coefficient, pKow
4.88
Heat of fusion
17.58 kJ/mol
Heat of vaporization
39.92 kJ/mol
Heat of combustion
-7851 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Insufficient information for classification.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acrid smoke and fumes.

Fire.
Flash Point,°C
200-220
Upper exp. limit, %
3.9
Lower exp. limit, %
0.6
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use foam, dry chemical, or carbon dioxide.
Fire potential
Flammable/combustible material. May be ignited by friction, heat, sparks or flames.
Hazards
When heated to decomposition, it emits acrid smoke and fumes.
Combustion products
Fire may produce irritating and/or toxic gases.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
NIOSH: occupational carcinogen OSHA: Select carcinogen
Poison_Class
3
Exposure effects
May cause cancer according to animal studies. Chronic effects may include leukocytosis and lengthened chronaxy of the leg muscle flexors.
   Ingestion
May cause digestive tract disturbances. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
   Inhalation
May be fatal if inhaled. Causes respiratory tract irritation. Inhalation of dust may cause respiratory tract irritation.
   Skin
Causes skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis. Dermal applications may cause hyperemia, weight loss, and hematopoietic changes.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1325
Response guide
Hazard class
4.1
Packing Group
II; III
 
USCG CHRIS Code
PYN
 
HS Code
2902 90 80