Pyridoxamine dihydrochloride

  • 4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride
  • 2-Methyl-3-hydroxy-4-aminomethyl-5-hydroxymethylpyridine dihydrochloride
Formula
C8H12N2O2.2HCl
Structure
Uses
Medication. Treatment of diabetic nephropathy.

Registry Numbers and Inventories.
CAS
524-36-7
EC (EINECS/ELINCS)
208-357-6
36/37/38
RTECS
UV1230000
RTECS class
Drug
Merck
13,7993
Beilstein/Gmelin
3632748
Beilstein Reference
5-22-12-00324
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H14Cl2N2O2
Formula mass
241.12
Melting point, °C
225 - 227

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Rubber gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Irritant. Irritating to eyes, respiratory system and skin.
   Inhalation
Material is irritating to mucous membranes and upper respiratory tract.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Transport.