Pyrrolidone

  • 2-Pyrrolidone
  • 2-Oxopyrrolidine
  • 2-Ketopyrrolidine
  • 2-Pyrrolidinone
Formula
C4H7NO
Structure
Description
Crystals from cold petroleum ether.
Uses
Intermediate in manufacture of polyvinylpyrrolidone & polypyrrolidone (polymer, formed in presence of alkaline catalysts), used as high-boiling solvent in petroleum processing, acrylonitrile mfr, in specialty printers inks, industrial solvent for polymers, chlordane, ddt, sorbitol, glycerol, iodine, sugars, as plasticizer & coalescing agent for acrylic-styrene emulsion-type floor polishes.

Registry Numbers and Inventories.
CAS
616-45-5
EC (EINECS/ELINCS)
210-483-1
R 21 36/38
S 26 36/37/39
RTECS
UY5715000
RTECS class
Drug; Mutagen; Reproductive Effector
UN (DOT)
2810
Merck
12,8200
Beilstein/Gmelin
105241
Beilstein Reference
5-21-06-00317
Swiss Giftliste 1
G-8869
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H7NO
Formula mass
85.11
Melting point, °C
24 - 26
Boiling point, °C
245
Vapor pressure, mmHg
0.009 (25 C)
Vapor density (air=1)
2.9
Critical temperature
529
Critical pressure
60.9
Density
1.1115 g/cm3 (20 C)
Solubility in water
1120 g/L
Viscosity
13.1 cp (25 C)
Refractive index
1.4806 (30 C)
Partition coefficient, pKow
-0.85
Heat of vaporization
73.7 kJ/mol
Heat of combustion
-2291 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents - strong acids _ strong bases _ - strong reducing agents _ moisture.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
138
Autoignition, °C
390
Upper exp. limit, %
13.1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
Slight risk when exposed to heat or flame. Can react with oxidizing materials.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
-
Exposure effects
   Ingestion
See Inhalation.
   Inhalation
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.
   Skin
Contact with molten substance may cause severe burns to skin and eyes. See Inhalation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Transport.
UN number
2810
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
HS Code
2933 79 00