p-Cresyl diphenyl phosphate

  • Diphenyl p-tolyl phosphate
Formula
C19H17O4P
Structure
Description
Odorless.
Uses
Plasticizer, extreme-pressure lubricant, hydraulic fluids, gasoline additive, food packaging isomeric mixt.

Registry Numbers and Inventories.
CAS
78-31-9
EC (EINECS/ELINCS)
201-104-0
Beilstein/Gmelin
2153781
Beilstein Reference
4-06-00-02130
Japan ENCS (MITI)
Listed

Properties.
Formula
C19H17O4P
Formula mass
340.32
Melting point, °C
18 - 20
Boiling point, °C
156 - 158 (0.002 torr)
Vapor density (air=1)
11.7
Density
1.208 g/cm3 (25 C)
Refractive index
1.5619 (24 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Respiratory protection (supplied-air respirator with full facepiece or self-contained breathing apparatus) should be available where these compounds are manufactured or used and should be worn in case of emergency and overexposure.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.

Fire.
Fire fighting
To fight fire: Water, foam, carbon dioxide, dry chemical.
Fire potential
Combustible. Slight fire risk when exposed to heat or flame.

Health.
Exposure effects
A delayed peripheral neuropathy of the dying back or peripheral axonopathy variety predominates. Between 10 and 40 days after exposure, abrupt onset of flaccid paralysis is noted. This may be followed by lower extremity spasticity with clonus, hyperreflexia, hypertonus, and a peculiar spastic gait. In severe cases the full extent of paralysis may not be reached until after 2 to 3 months. Recovery is variable. Mortality is usually low and approximately 5% of victims may remain paralyzed. TOCP produced toxic effects on both male and female REPRODUCTIVE SYSTEMS when Long-Evans rats were given doses of 0 to 400 mg/kg by gavage prior to, and during breeding. Spermatotoxic effects, includes reduced motility, concentration, velocity, and abnormal morphology. Damage to ovarian and uterine tissue also 1999).
   Ingestion
Abdominal pain, nausea, and vomiting often occur. Diarrhea may last several weeks.
   Skin
The soles of the feet and palms may be cold, cyanotic, and profusely diaphoretic.

First aid
 
   Ingestion
Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.