p-Fluoroaniline

  • 4-Fluorobenzenamine
  • 4-Fluoroaniline
Formula
4-(F)C6H4NH2
Structure
Description
Liquid.
Uses
Intermediate in manufacture of herbicides & plant growth regulators.

Registry Numbers and Inventories.
CAS
371-40-4
EC (EINECS/ELINCS)
206-735-5
EC Class
harmful, irritant
R 20/21/22 36/38
S 26 36/37/39
RTECS
BY1575000
RTECS class
Mutagen; Primary Irritant
UN (DOT)
2941
Merck
13,4196
Beilstein/Gmelin
742030
Beilstein Reference
4-12-00-01104
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H6FN
Formula mass
111.12
Melting point, °C
-1
Boiling point, °C
187
Vapor pressure, mmHg
0.6 (25 C)
Density
1.1613 g/cm3 (17 C)
Solubility in water
33 g/L
Viscosity
3.03 cp (20 C)
Refractive index
1.5359 (17 C)
pKa/pKb
9.34 (pKb)
Partition coefficient, pKow
1.15
Heat of vaporization
42.5 kJ/mol
Heat of combustion
-3262 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Keep from contact with oxidizing materials.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Disposal code
2
Stability
No data.
Incompatibilities
Acids, acid chlorides, strong oxidizing agents, acid anhydrides, chloroformates.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.

Fire.
Flash Point,°C
74
Autoignition, °C
>600
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Combustible Liquid. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis.
   Ingestion
Harmful if swallowed. May cause irritation of the digestive tract.
   Inhalation
May cause respiratory tract irritation. May be harmful if inhaled.
   Skin
Causes skin irritation. May be harmful if absorbed through the skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2941
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
FLA
 
HS Code
2921 42 10