p-Fluorophenacyl chloride

  • a-Chloro-p-fluoroacetophenone
  • 2-Chloro-1-(4-fluorophenyl)ethanone
  • 2-Chloro-1-(4'-fluorophenyl)ethanone
Formula
C8H6ClFO
Structure
Description
Yellow-beige crystals.

Registry Numbers and Inventories.
CAS
456-04-2
EC (EINECS/ELINCS)
207-256-4
R 36/37/38
S 26 36/37/39
RTECS
AM6550000
RTECS class
Other
UN (DOT)
1693
Beilstein/Gmelin
637860
Beilstein Reference
4-07-00-00642

Properties.
Formula
C8H6ClFO
Formula mass
172.58
Melting point, °C
45
Boiling point, °C
247
Vapor pressure, mmHg
0.03 (25 C)
Solubility in water
Insoluble
Partition coefficient, pKow
2.16
Heat of vaporization
48.4 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.

Fire.
Flash Point,°C
103
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Containers may explode when heated. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Do NOT get water inside containers. For large fires, use water spray, fog or regular foam. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
May burn but not readily ignited.
Hazards
Containers may explode when heated.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cardiac disturbances. May cause central nervous system effects.
   Inhalation
Causes respiratory tract irritation. May cause cardiac abnormalities. Can produce delayed pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.
   Skin
Causes skin irritation.
   Eyes
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. Lachrymator. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
1693
Response guide
Hazard class
6.1
Packing Group
II