p-Nitro-N,N-dimethylaniline

  • N,N-Dimethyl-p-nitroaniline
  • p-Nitrodimethylaniline
  • N,N-Dimethyl-4-nitrobenzenamine
  • p-(Dimethylamino)nitrobenzene
Formula
C8H10N2O2
Structure
Description
Bright yellow powder with an aniline-like odor.

Registry Numbers and Inventories.
CAS
100-23-2
EC (EINECS/ELINCS)
202-832-1
R 20/21/22
S 22 36/37
RTECS
BX7035000
RTECS class
Other
UN (DOT)
1661
Beilstein/Gmelin
638087
Beilstein Reference
4-12-00-01616
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C8H10N2O2
Formula mass
166.20
Melting point, °C
159 - 160
Boiling point, °C
288
Vapor pressure, mmHg
0.0025 (25 C)
Density
1,179 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
0.102 cp (172 C)
Surface tension
34.7 g/s2 (172 C)
pKa/pKb
13.26 (pKb)
Partition coefficient, pKow
2.61
Heat of vaporization
54.7 kJ/mol
Heat of combustion
-4539 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
128
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
2 ppm TWA ACGIH
Exposure effects
May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death.
   Ingestion
May cause irritation of the digestive tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. Overexposure may cause methemoglobinemia. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1661
Response guide
Hazard class
6.1
Packing Group
II