Light yellow crystalline solid. Sweet odor.
p-Chloronitrobenzene is used to manufacture p-nitrophenol, p-nitroaniline, p-aminophenol, phenacetin, acetominophen, parathion and other agricultural chemicals, rubber chemicals, antioxidants, oil additives and dapsone (an antimalarial drug).
Registry Numbers and Inventories.
EC Index Number
Toxic; Danger of cumulative effects; Dangerous for the Environment
R 23/24/25 33 51/53
S 28 36/37 45 61
Tumorigen; Mutagen; Reproductive Effector
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
0.09 (25 C)
Vapor density (air=1)
1.52 g/cm3 (20 C)
Solubility in water
0.21 g/L (20 C)
1.07x10-3 pa-s @ 356.65 deg K
34.3 g/s2 (90 C)
1.5376 (100 C)
Partition coefficient, pKow
Heat of vaporization
Heat of combustion
Hazards and Protection.
Store in a cool, dry place. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with skin and eyes. Do not ingest or inhale.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.
Stable under normal temperatures and pressures.
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Upper exp. limit, %
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
This compound is combustible.
Containers may explode when heated.
Fire may produce irritating, corrosive and/or toxic gases.
TLV: 0.1 ppm; 0.64 mg/m3 (as TWA) A3 (skin) (ACGIH 1997). OSHA PEL: TWA 1 mg/m3 skin NIOSH REL: Ca See Appendix A skin NIOSH IDLH: Potential occupational carcinogen 100 mg/m3
May cause liver and kidney damage. Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis. May cause anemia and other blood cell abnormalities. May cause fatigue, dizziness, headache, insomnia and weight loss.
Harmful if swallowed. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May cause central nervous system depression.
May cause effects similar to those described for ingestion. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood.
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Causes eye irritation.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
USCG CHRIS Code
2904 90 85