p-Phenetidine

  • p-Aminophenyl ethyl ether
  • 4-Ethoxybenzenamine
  • 4-Aminophenetole
  • 4-Ethoxyaniline
  • Benzenamine, 4-ethoxy
Formula
4-(C2H5O)C6H4NH2
Structure
Description
Colorless to dark red liquid.
Uses
Production of acetophenetidine, phenocoll, dulcin, dyes.

Registry Numbers and Inventories.
CAS
156-43-4
EC (EINECS/ELINCS)
205-855-5
EC Index Number
612-039-00-6
EC Class
Toxic; Danger of cumulative effects
R 23/24/25 33
S 28 36/37 45
RTECS
SI6465500
RTECS class
Drug; Mutagen; Primary Irritant
UN (DOT)
2311
Merck
12,7373
Beilstein/Gmelin
606666
Beilstein Reference
4-13-00-01017
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H11NO
Formula mass
137.18
Melting point, °C
4
Boiling point, °C
254
Vapor pressure, mmHg
0.02 (25 C)
Vapor density (air=1)
4.73
Density
1.0613 g/cm3 (15 C)
Solubility in water
5-10 mg/ml
Refractive index
1.5572 (15.9 C)
pKa/pKb
8.74 (pKb)
Partition coefficient, pKow
1.28
Heat of vaporization
49.1 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. Store protected from light and air.
Handling
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light. Store protected from air.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures. Air sensitive Light sensitive.
Incompatibilities
Acids - acid chlorides - acid anhydrides - chloroformates - strong oxidizing agents - light - air.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
115
Autoignition, °C
460
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
This compound is combustible.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
There is a danger of cumulative effects.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. Effects of inhalation may be delayed.
   Skin
Causes mild skin irritation. May be absorbed through the skin. Effects of contact may be delayed.
   Eyes
Causes moderate eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2311
Response guide
Hazard class
6.1
Packing Group
III
 
HS Code
2922 22 00