p-Phenylenediamine

  • 1,4-Phenylenediamine
  • 1,4-Diaminobenzene
  • 1,4-Benzenediamine
  • p-Aminoaniline
Formula
C6H8N2
Structure
Description
White to light purple solid.
Uses
Dyeing furs, also in photochemical measurements, accelerating vulcanization, Manufacture azo dyes.

Registry Numbers and Inventories.
CAS
106-50-3
EC (EINECS/ELINCS)
203-404-7
EC Index Number
612-028-00-6
EC Class
Toxic; Irritant; Sensitising; Dangerous for the Environment
R 23/24/25 36 43 50/53
S 28 36/37 45 60 61
RTECS
SS8050000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Human Data; Primary Irritant
UN (DOT)
1673
Merck
12,7439
Beilstein/Gmelin
742029
Beilstein Reference
4-13-00-00104
Swiss Giftliste 1
G-2050
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H8N2
Formula mass
108.14
Melting point, °C
139 - 141
Boiling point, °C
267
Vapor pressure, mmHg
0.008 (25 C)
Vapor density (air=1)
3.72
Saturation Concentration
Less than 1300 ppm (0.1%) at 20 C (calculated)
Density
1.251 g/cm3
Solubility in water
47 g/L
pKa/pKb
7.83 (pKb)
Partition coefficient, pKow
-0.25
Heat of fusion
24.9 kJ/mol
Heat of vaporization
50.5 kJ/mol
Heat of combustion
-3501 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Material darkens on exposure to air.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid contact with heat, sparks and flame. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Remove all sources of ignition.
Disposal code
9
Stability
Stable under normal temperatures and pressures. Substance undergoes color change upon exposure to light and air.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
136
Autoignition, °C
400
Upper exp. limit, %
9.8
Lower exp. limit, %
1.3
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
Combustible when exposed to heat or flame.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
TLV: 0.1 mg/m3 A4 (as TWA) (ACGIH 1997). MAK: 0.1 mg/m3; H, S, IIIB (1996) OSHA PEL: TWA 0.1 mg/m3 skin NIOSH REL: TWA 0.1 mg/m3 skin NIOSH IDLH: 25 mg/m3
Poison_Class
2
Exposure effects
Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated exposure may cause adverse reproductive effects.
   Ingestion
Harmful if swallowed. May cause irritation of the digestive tract. May cause liver and kidney damage. Ingestion may cause gastritis, vertigo, tremors, convulsions, and possible coma.
   Inhalation
Dust is irritating to the respiratory tract. May cause asthmatic attacks due to allergic sensitization of the respiratory tract. May cause rhinitis.
   Skin
Causes skin irritation. May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May produce eczematoid contact dermatitis
   Eyes
Causes eye irritation. May cause conjunctivitis and keratitis.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1673
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
PDM
 
HS Code
2921 51 19
 
Std. Transport #
4915233