Quinine sulfate dihydrate

  • Quinine, sulfate (2:1), dihydrate
  • Cinchonan-9-ol, 6'-methoxy-, (8a,9R)-, sulfate (2:1) (salt), dihydrate
Formula
C40H48N4O4.H2SO4.2H2O
Structure
Description
White to off-white solid.
Uses
Flavoring.

Registry Numbers and Inventories.
CAS
6119-70-6
EC (EINECS/ELINCS)
212-359-2
R 22 42/43
S 22 36/37 45
RTECS
VA8440000
UN (DOT)
3335
Merck
12,3822
Beilstein/Gmelin
6113937
Beilstein Reference
5-23-13-00395
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
2C20H24N2O2*H2O4S*2H2O
Formula mass
782.94
Melting point, °C
219
Vapor pressure, mmHg
11 (23 C)
Density
1.36 g/cm3

Hazards and Protection.
Storage
Store in a tightly closed container. Store protected from light. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with skin and eyes. Keep container tightly closed. Do not ingest or inhale. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures. May decompose when exposed to light. Light sensitive.
Incompatibilities
Strong oxidizing agents, direct light.
Decomposition
Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause muscle tremor and impaired motor function. May cause systemic toxic effects on the heart, liver, and kidneys. Exposure may cause anemia and other blood abnormalities. May cause nausea and vomiting. May cause acute hepatitis. May cause allergic reaction. Ingestion can cause blurred vision, narrowing of the visual field, or blindness.
   Inhalation
May cause respiratory tract irritation. May cause effects similar to those described for ingestion. May cause an allergic response.
   Skin
Causes skin irritation. May be harmful if absorbed through the skin. May cause an allergic reaction in certain individuals. May cause sensitization by skin contact.
   Eyes
Causes eye irritation. May cause blindness.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
3335
Response guide