Quinuclidine

  • 1,4-Ethanopiperidine
  • 1,4-Ethylenepiperidine
  • 1-Azabicyclo[2.2.2]octane
  • [2,2,2]-Azabicyclooctane
Formula
C7H13N
Structure
Description
slightly beige crystals
Uses
Employed in studies on the OsO4-catalyzed dihydroxylation of olefins.

Registry Numbers and Inventories.
CAS
100-76-5
EC (EINECS/ELINCS)
202-887-1
24/25 38 41
26 36/37/39 45
RTECS
CL5594625
RTECS class
Primary Irritant
UN (DOT)
2811
Merck
12,8265
Beilstein/Gmelin
103111
Beilstein Reference
5-20=04=00335
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
Korea ECL
Listed

Properties.
Formula
C7H13N
Formula mass
111.19
Boiling point, °C
150
Sublimation point, °C
159
Vapor pressure, mmHg
4 (25 C)
Density
1.025 g/cm3
Solubility in water
Very soluble
pKa/pKb
2.89 (pKb)
Partition coefficient, pKow
1.38
Heat of vaporization
38.6 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place. Incompatible Materials: Absorbs carbon dioxide from air.
Protection
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Acids, Acid chlorides, Acid anhydrides, Oxidizing agents, Chloroformates.
Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Flash Point,°C
37
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
0
 
 
Reactivity
1
 

Health.
Exposure effects
Toxic in contact with skin and if swallowed. Irritating to skin. Risk of serious damage to eyes.
   Ingestion
Toxic if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be toxic by inhalation.
   Skin
Causes skin irritation. Toxic if absorbed through skin.
   Eyes
Causes severe eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
II