Resourcinol

  • 1,3-Dihydroxybenzene
  • 3-Hydroxyphenol
  • 1,3-Benzenediol
  • m-Benzenediol
  • m-Hydroxyphenol
Formula
C6H4(OH)2
Structure
Description
White crystal flakes or powder, hygroscopic.
Uses
Used to make plastics and pharmaceuticals.

Registry Numbers and Inventories.
CAS
108-46-3
EC (EINECS/ELINCS)
203-585-2
EC Index Number
604-010-00-1
EC Class
Harmful; Irritant; Dangerous for the Environment
R 22 36/38 50
RTECS
VG9625000
RTECS class
Tumorigen; Drug; Mutagen; Human Data; Primary Irritant
UN (DOT)
2876
Merck
12,8323
Beilstein/Gmelin
906905
Beilstein Reference
4-06-00-05658
RCRA
U201
EPA OPP
71401
Swiss Giftliste 1
G-2834
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H6O2
Formula mass
110.11
Melting point, °C
109 - 111
Boiling point, °C
281
Vapor pressure, mmHg
0.0023 (25 C)
Vapor density (air=1)
3.8
Saturation Concentration
0.3 ppm at 25 C (calculated)
Odor Threshold Odor threshold 6.0 mg/L
Density
1.272 g/cm3
Solubility in water
Soluble
Viscosity
3.76 cp (141 C)
Surface tension
41.6 g/s2 (184 C)
Refractive index
1.5404 (20 C)
pKa/pKb
9.32 (pKa)
Partition coefficient, pKow
0.80
Heat of fusion
20.9 kJ/mol
Heat of vaporization
54.0 kJ/mol
Heat of combustion
-2848 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from light. Store under an inert atmosphere.
D1B D2B
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Store protected from light. Handle under an inert atmosphere. Store protected from air.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective clothing to prevent skin exposure. Clothing: Wear appropriate protective gloves to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Place under an inert atmosphere.
Stability
Stable at normal temperatures in tightly closed containers under an inert atmosphere. Substance undergoes color change upon exposure to light and air. Volatile in steam. May undergo auto-oxidation at 25 C.
Incompatibilities
Strong oxidizing agents, bases, acid chlorides, iron, nitric acid, acid anhydrides, albumin, alkalies, iron salts, antipyrine, acetanilide, air, menthol, urethane, spirit nitrous ether, camphor.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
127
Autoignition, °C
605
Upper exp. limit, %
9.8
Lower exp. limit, %
1.6
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Dusts at sufficient concentrations can form explosive mixtures with air. Extinguishing media: Water spray may cause frothing. Cool containers with flooding quantities of water until well after fire is out. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.
Fire potential
Slightly flammable.
Hazards
Containers may explode.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 10 ppm; 45 mg/m3 (as TWA); 20 ppm; 90 mg/m3 (STEL) (ACGIH 1997). MAK: 10 ppm; 45 mg/m3 (1997). NIOSH REL: TWA 10 ppm (45 mg/m3) ST 20 ppm (90 mg/m3)
Poison_Class
3
Exposure effects
May cause liver and kidney damage. Repeated exposure may cause sensitization dermatitis. Repeated exposure may cause damage to the spleen. Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May cause methemoglobinemia, cyanosis, convulsions, and death.
   Inhalation
Dust is irritating to the respiratory tract. Causes irritation of the mucous membrane and upper respiratory tract.
   Skin
Causes moderate skin irritation. May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. If absorbed, may cause symptoms similar to those for ingestion. Resorcinol has been known to cause hyperemia, itch, dermatitis, edema, and corrosion.
   Eyes
Contact with eyes may cause severe irritation, and possible eye burns. Contact of the eye with resorcinol has caused necrosis and corneal perforation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2876
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
RSC
 
HS Code
2907 21 00
 
Std. Transport #
4925136