Riboflavin

  • Beflavine
  • Benzo(g)pteridine-2,4(3H,10h)-dione, 7,8-dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)-6,7-dimethyl-9-d-ribitylisoalloxazine
  • 6,7-Dimethyl-9-D-ribitylisoalloxazine
  • Isoalloxazine, 7,8-dimethyl-10-D-ribityl
  • Riboflavine
  • Vitamin B2
Formula
C17H20N4O6
Structure
Description
Fine orange-yellow needles. or powder.
Uses
inhibitor of poly(ethylene glycol) oxidation

Registry Numbers and Inventories.
CAS
83-88-5
EC (EINECS/ELINCS)
201-507-1
RTECS
VJ1400000
RTECS class
Drug; Mutagen
Merck
12,8367
Beilstein/Gmelin
97825
Beilstein Reference
4-26-00-02542
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C17H20N4O6
Formula mass
376.37
Melting point, °C
280
Solubility in water
0.1 g/L
pKa/pKb
4.32 (pKa)
Partition coefficient, pKow
-1.46

Hazards and Protection.
Storage
Store in a tightly closed container. Store below 40C. Store protected from light. Store in a cool, dry area away from incompatible substances.
Handling
Use with adequate ventilation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures. May decompose on exposure to moist air or water. Darkens on exposure to light.
Incompatibilities
Strong oxidizing agents, reducing agents, bases, metallic salts, calcium, moisture, direct light.
Decomposition
Nitrogen oxides, carbon monoxide, oxides of phosphorus, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Dust can be an explosion hazard when exposed to heat or flame. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
F (Not subject to toxicity classification)
Exposure effects
   Ingestion
Ingestion of large amounts may cause gastrointestinal irritation. Low hazard for usual industrial handling.
   Inhalation
May cause respiratory tract irritation. Low hazard for usual industrial handling.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2936 23 00