Rutecarpine

  • 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
  • Rhetine
  • Rutaecarpine
Formula
C18H13N3O
Structure
Description
White solid.
Uses
Inhibits platelet aggregation; vasoldilator.

Registry Numbers and Inventories.
CAS
84-26-4
UN (DOT)
2811
Merck
12,8451

Properties.
Formula
C18H13N3O
Formula mass
287.32
Melting point, °C
259.5 - 260
Boiling point, °C
550
Vapor pressure, mmHg
3.8E-12 (25 C)
Density
1.45 g/cm3 (20 C)
Solubility in water
26 mg/L (25 C)
pKa/pKb
8.62 (pKb)
Partition coefficient, pKow
2.03
Heat of vaporization
83.01 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C. Keep container tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
286
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Target organs/systems: Cardiovascular system. Central nervous system. Blood.
   Ingestion
Toxic if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
Causes irritation. May be harmful if absorbed through the skin.
   Eyes
May cause irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
III