Sarin

  • GB (NATO military designation)
  • Isopropoxymethylphosphoryl fluoride
  • Isopropyl methylphosphonofluoridate
Formula
C4H10FO2P
Structure
Description
A colorless liquid. Almost no odor in pure state.
Uses
Chemical warfare agent. G series nerve agent.

Registry Numbers and Inventories.
CAS
107-44-8
RTECS
TA8400000
RTECS class
Drug; Human Data
UN (DOT)
2810
Merck
12,8520
Beilstein/Gmelin
1750114
Beilstein Reference
4-04-00-03507
EPA OPP
605701
Swiss Giftliste 1
G-4617
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C4H10FO2P
Formula mass
140.09
Melting point, °C
-57.2
Boiling point, °C
147
Vapor pressure, mmHg
5.7 (25 C)
Vapor density (air=1)
4.86
Density
1.1 g/cm3 (20 C)
Solubility in water
Very soluble
Partition coefficient, pKow
0.32
Heat of vaporization
36.8 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Rapidly hydrolyzed by dilute aqueous sodium hydroxide or sodium carbonate forming relatively non-toxic products. Water alone removes the fluorine atom producing a non-toxic acid. Decontaminants include bleach slurry, dilute alkali, hot soapy water, steam and ammonia.
Stability
Unstable in the presence of water. Fairly stable in steel containers at 65 C. Stability improves with increasing purity.
Incompatibilities
Corrosive to steel.

Fire.
Flash Point,°C
42
Fire fighting
Protective clothing and respiratory protection.Extinguish with foam, carbon dioxide, and dry chemical
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Non-flammable. Acidic conditions produce hydrogen fluoride; alkaline conditions produce isopropyl alcohol and polymers. When heated to decomposition or reacted with steam, it emits very toxic fumes of fluorides and oxides of phosphorus. Slightly corrosive to steel. Hydrolyzed by water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
1
Exposure effects
Effects from vapor exposure begin to appear 30 seconds to 2 minutes after exposure. With liquids, there is almost always a latent period with no visible effects between the time of exposure and the onset of symptoms. Effects from liquid exposure begin to appear from several minutes up to 18 hours after exposure. Onset of symptoms from exposure to large amounts of liquid agent may appear as rapidly as 1 minute after exposure. Generally, the more rapid the onset of symptoms, the larger the amount of agent involved in the exposure.
   Ingestion
See Inhalation.
   Inhalation
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.
   Skin
The symptoms in normal order of appearance are running nose; tightness of chest; dimness of vision and pinpointing of the eye pupils (myosis); difficulty in breathing; drooling and excessive sweating; nausea, vomiting; cramps and involuntary defecation or urination; twitching, jerking, and staggering; and headache, confusion, drowsiness, coma, and convulsion. These symptoms are followed by cessation of breathing and death.
   Eyes
Constriction of the pupil, tearing, and blurred or dim vision are common clinical findings. Occasionally prolonged dialation of the pupils may occur in severe poisonings. Excessive salivation commonly occurs.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Nerve agent vapors are heavier than air, which means that they will sink into low terrain and basements. Monitor ecg and adequacy of respirations and ventilation; supplemental oxygenation, frequent suctioning of secretions, endotracheal intubation, and assisted ventilation may be required.
   Skin
Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
2810
Response guide
Hazard class
6.1
PRTC
T
Packing Group
I; II; III
 
USCG CHRIS Code
SIN