- 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate
- 6-beta,7-beta-Epoxy-4-alpha-tropanyl S-(-)-tropate
- Epoxytropine tropate
- 6,7-Epoxytropine tropate
Anticholinergic scopolamine & salts.
Registry Numbers and Inventories.
EC Index Number
Drug; Mutagen; Reproductive Effector; Human Data
Melting point, °C
Solubility in water
soluble in 9.5 parts water @ 15 C
Partition coefficient, pKow
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Easily hydrolyzed by acids or alkalies; decomp on standing. Sensitive to light and air. Hydrobromide trihydrate.
Strong oxidizing agents.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Vital sign changes include rapid heart rate and elevated blood pressure. Both elevated body temperature and reduced body temperature have been reported, but elevated body temperature is more common. Toxic psychosis (disorientation, delirium, hallucinations, and paranoia associated with anxiety, agitation, and hyperactivity) has been reported. Memory loss has also been noted as a toxic anticholinergic effect. Seizures, dystonic reactions, and dyskinesias may occur at recommended doses. Severe poisoning may produce coma, medullary paralysis, and death.
Decreased gastric motility, diminished bowel sounds, esophageal atony and dilatation, colonic distention, and paralytic ileus may occur as a result of anticholinergic toxicity.
Respiratory depression, respiratory failure, and aspiration may occur in severe overdoses.
Warm red skin with decreased sweating is common. Delayed hypersensitivity has also been reported.
Warm red skin, decreased sweating, dry oral mucous membranes, and widely dilated pupils are common.
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.