Simazine

  • 2-Chloro-4,6-bis(ethylamino)-S-triazine
  • 2,4-bis(ethylamino)-6-chloro-S-triazine
  • 2-Chloro-4,6-bis(ethylamino)-1,3,5-triazine
  • Princep
  • Herbex
  • Symazine
Formula
C7H12ClN5
Structure
Description
White to off-white crystalline powder NTP, 1992).
Uses
Selective systemic herbicide. Control of most germinating annual grasses and broad-leaved weeds.

Registry Numbers and Inventories.
CAS
122-34-9
EC (EINECS/ELINCS)
204-535-2
EC Index Number
612-088-00-3
EC Class
Carcinogenic Category 3; Dangerous for the Environment
R 40 50/53
S 36/37 46 60 61
RTECS
XY5250000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
2763
Merck
12,8681
Beilstein/Gmelin
10895
Beilstein Reference
4-26-00-01208
EPA OPP
80807
Swiss Giftliste 1
G-2039
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H12ClN5
Formula mass
201.66
Melting point, °C
126
Boiling point, °C
366
Vapor pressure, mmHg
1.5E-5 (25 C)
Vapor density (air=1)
1.302
Density
1.302 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
12.38 (pKb)
Partition coefficient, pKow
2.18
Heat of vaporization
61.2 kJ/mol

Hazards and Protection.
Storage
Keep in well ventilated area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
The use of personal protective equipment such as glasses, synthetic gloves and NIOSH approved breathing apparatus is important.
Respirators
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Small spills/leaks
Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
Stable.
Decomposition
When heated to decomposition it emits very toxic fumes of hydrogen chloride and nitrous oxides.

Fire.
Flash Point,°C
175
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is nonflammable
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
4
Exposure effects
Coma was reported following ingestion of an herbicide containing atrazine, aminotriazole, ethylene glycol, and formaldehyde. Muscle tremors, tetany, and ataxia have been reported in animals following ingestions of triazine herbicides.
   Inhalation
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.
   Skin
Avoid any skin contact. See Inhalation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2763
Response guide
Hazard class
6.1
Packing Group
I; II; III