Sodium levothyroxine pentahydrate
- L-Thyroxine sodium salt pentahydrate
- 3',3,5',5-Tetraiodo-L-thyronine sodium salt pentahydrate
- L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt, pentahydrate
Odorless beige grey solid
The major hormone derived from the thyroid gland. It is used to treat hypothyroidism.
Registry Numbers and Inventories.
Melting point, °C
Vapor density (air=1)
2.381 g/cm3 (20 C)
Hazards and Protection.
Store in a cool, dry place. Hormones and antibiotics room. Keep containers tightly closed.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stable under normal temperatures and pressures.
Explosion hazard when mixed with strong oxidizers.
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen iodide, iodide ions (I-).
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Extinguishing media: Use alcohol foam, carbon dioxide, or water spray when fighting fires involving this material.
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Contact with metals may evolve flammable hydrogen gas.
Fire may produce irritating, corrosive and/or toxic gases.
Chronic exposure can lead to iodism characterized by salivation, nasal discharge, sneezing, conjunctivitis, fever, laryngitis, bronchitis, stomatitis, and skin rashes.
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause thyroid abnormalities. Ingestion increases the metabolic rate causing warm, flushed and moist skin, muscular weakness, rapid heart rate, insomnia, nervousness, increased metabolism and weight loss. Effects may be delayed.
May cause respiratory tract irritation. May cause effects similar to those described for ingestion.
May cause skin irritation.
May cause severe eye irritation.
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
I; II; III