Sodium orthoarsenate

  • Sodium arsenate
  • Disodium hydrogen arsenate
Formula
Na2HAsO4
Structure
Description
Powder. Odorless.
Uses
All registered products for nonwood use that contain the inorganic arsenicals sodium arsenate are cancelled and applications denied. References: 53 fr 5524 (22488), 53 fr 24787 (63088).

Registry Numbers and Inventories.
CAS
7778-43-0
EC (EINECS/ELINCS)
231-902-4
RTECS
CG0875000
RTECS class
Mutagen
UN (DOT)
1685
Merck
12,8720
Beilstein/Gmelin
37330 (G)
RCRA
D004
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
AsHNa2O4
Formula mass
185.91
Melting point, °C
57
Density
1.87 g/cm3 (20 C)
Solubility in water
394 g/L (21 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Effloresces in warm air sodium arsenate heptahydrate.
Incompatibilities
When water soln of arsenicals are in contact with active metals such as arsenic, iron, aluminum, zinc, highly toxic fumes of arsenic including arsine are released.
Decomposition
Dangerous when heated to decomp. Emits toxic fumes of arsenic including arsine.

Fire.
Fire fighting
Use method most appropriate to fight surrounding fire.
Fire potential
Non-Combustible
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
TLV (as As): ppm; 0.2 mg/m3 (ACGIH 1991-1992).
Carcinogin
O, G-A1, I-1, N-1, CP65
Exposure effects
Patients may rapidly become hypotensive. Rapid heart rate may develop secondary to pain, hypovolemia, cardiac effects of arsenic, or anxiety. Toxic delirium and encephalopathy are possible complications. Peripheral neuropathy is common. Seizures may occur. Sodium arsenate is teratogenic or fetotoxic in mice, rats, and hamsters. Fetotoxicity and fetal death are possible, but arsenic is NOT likely to be a significant risk to human reproduction at permissible occupational exposure limits. <br>Arsenic can cross the placenta. Arsenic is excreted in the breast milk in both experimental animals and humans. <br>Systemic toxicity was present before any effects were noted on the testes.
   Ingestion
Early symptoms within hours following arsenic ingestion include abdominal pain, vomiting, profuse bloody or watery (rice-water-like) diarrhea, pain in the extremities and muscles, weakness, and flushing of the skin.
   Inhalation
Acute respiratory failure was seen in a patient with severe arsenic poisoning. Pulmonary edema may occur and be life-threatening. Adult respiratory distress syndrome (ards) has been reported.
   Skin
Avoid any skin contact. See Inhalation.
   Eyes
Inflammation of the eye, photophobia, dimness of vision, diplopia, and tearing may occur. A garlic-like odor may be detected on the breath.

First aid
 
   Ingestion
Gastric decontamination - aggressive decontamination with gastric lavage is recommended. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove and isolate contaminated clothing and shoes. Remove material from skin immediately. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
1685
Response guide
Hazard class
6.1
Packing Group
II