Solanidine

  • Solatubine
  • Solanid-5-en-3-beta-ol
  • 1H-Naphth[2',1':4,5]indeno[1,2-b]indolizine, solanid-5-en-3-ol deriv.
Formula
C27H43NO
Structure
Uses
Used as starting material in the synthesis of steroid hormones, it has to be transformed into 16-dehydropregnenolon.

Registry Numbers and Inventories.
CAS
80-78-4
EC (EINECS/ELINCS)
201-309-5
23/24/25
22 36/37/39 45
RTECS
WF0500000
RTECS class
Drug; Mutagen
UN (DOT)
1544
Merck
12,8852
Beilstein/Gmelin
45370
Beilstein Reference
4-21-00-01398

Properties.
Formula
C27H43NO
Formula mass
397.64
Melting point, °C
215 - 218
Boiling point, °C
503
Vapor pressure, mmHg
3E-12 (25 C)
Solubility in water
Insoluble
pKa/pKb
2.32 (pKb)
Heat of vaporization
88.9 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Carefully sweep up and remove. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
224
Fire fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-Combustible
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Toxic by inhalation, in contact with skin and if swallowed. Target organ(s): Nerves.
   Inhalation
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.
   Skin
Avoid any skin contact. See Inhalation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
1544
Response guide
Hazard class
6.1
Packing Group
II