Sorbitol

  • D-Glucitol
  • D-Sorbitol
  • Hexahydric alcohol
  • Sorbite
  • Clucitol
Formula
C6H14O6
Structure
Description
Odorless, white crystalline powder.
Uses
In manufacture of sorbose, ascorbic acid, propylene glycol, synthetic plasticizers & resins, moisture conditioner on printing rolls, in leather, in writing inks, in candy production, in antifreeze mixtures with glycerol or glycols incr absorption of pharmaceutical prepn, pharmaceutic aid (sweetening agent, tablet excipient). Marker for drug-induced decreases iof variable dureation in liver blood flow.

Registry Numbers and Inventories.
CAS
50-70-4
EC (EINECS/ELINCS)
200-061-5
RTECS
LZ4290000
RTECS class
Mutagen; Human Data
Merck
12,8873
Beilstein/Gmelin
1721899
Beilstein Reference
4-01-00-02839
EPA OPP
8
Swiss Giftliste 1
G-3903
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H14O6
Formula mass
182.17
Melting point, °C
94 - 98
Boiling point, °C
295
Vapor pressure, mmHg
24 (25 C)
Critical temperature
543
Critical pressure
67.4
Density
1.524 g/cm3 (20 C)
Solubility in water
550 g/L (20 C)
Viscosity
110 cp (25 C)
Refractive index
1.45831 (20 C)
Dielectric constant
33.5 (80 C)
pKa/pKb
13.6 (pKa)
Partition coefficient, pKow
-2.20
Heat of fusion
28.05 kJ/mol
Heat of vaporization
132.4 kJ/mol
Heat of combustion
-3026 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Wash hands before eating. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Use with adequate ventilation. Do not allow contact with water. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
>100
Autoignition, °C
> 150
Upper exp. limit, %
12.4
Lower exp. limit, %
1.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use agent most appropriate to extinguish fire. Do NOT get water inside containers.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
-
Exposure effects
   Ingestion
May cause irritation of the digestive tract. Low hazard for usual industrial handling.
   Inhalation
May cause respiratory tract irritation. Low hazard for usual industrial handling. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Wash mouth out with water. Get medical aid if irritation or symptoms occur.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Transport.
USCG CHRIS Code
SBT
 
20 Alcohols, Glycols
HS Code
2905 44 91